Clay Siegall: The Revolutionary Mastermind in Cancer Therapy

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Clay B. Siegall, Ph.D., is the cofounder, chief executive officer, and president of Seattle Genetics which was found in 1998. He is also the chairman of the board. His company is focused on targeted cancer therapies. He also built Seattle Genetics on a foundation of rigorous research, scientific innovation, drug development practices, and a passion in helping patients. Dr. Clay Siegall also guided his organization to it’s present leadership position in securing the 2011 FDA approval for ADCETRIS (brentuximab vedotin), the first ADC product. And now, ADCETRIS is under collaboration with Takeda Pharmaceutical Company, and this company is approved in over 65 countries.

There are other multiple strategic licenses that Seattle Genetics has entered for their ADC technology, including AbbVie, Pfizer, Genentech (Roche), and GlaxoSmithKline. And as a result, this company has generated over $350 million to date, and there are over 20 ADCs in clinical development across collaborator and internal programs by utilizing Seattle Genetics’ technology. And other Seattle Genetics has capital raising activities in which have secures over $1.2 billion through private and public financings which include the organization’s initial public offering in 2001.

Dr. Siegall’s Other Works

Before cofounding Seattle Genetics, Dr. Siegall worked for the Bristol-Myers Squibb Pharmaceutical Research Institute of Health from 1991 to 1997. From 1988 to 1991, he worked for the National Cancer Institute, National Institutes of Health. Dr. Siegall is on the board of directors for the Alder BioPharmaceuticals, Ultragenyx Pharmaceutical, and Washington Roundtable. He also has won several awards, including the 2012 Pacific Northwest Ernst & Young Entrepreneur of the Year, and the University of Maryland Alumnus of the Year for Computer, Math, and Natural Sciences in 2013. Dr. Siegall has also published over 70 publications, and he held 15 patents. And with his educational achievements, he earned a Ph.D. in Genetics from the George Washington University, and a B.S. degree in Zoology from the University of Maryland. Even with his WordPress blog, he has created several writings that are relatable to cell therapy and cancer. However, he also has written blogs, such as dreams, the flaws of science and undermining good medicine, and so forth.


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